Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study

• Main Authors: Júlia Kudláčová (Author), Lenka Kotrchová (Author), Libor Kostka (Author), Eva Randárová (Author), Marcela Filipová (Author), Olga Janoušková (Author), Jun Fang (Author), Tomáš Etrych (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanomedicines are a novel class of therapeutics that benefit from the nano dimensions of the drug carrier. These nanosystems are highly advantageous mainly within cancer treatment due to their enhanced tumor accumulation. Monolayer tumor cells frequently used in routine preclinical assessment of nan...