Distribution in Rat Blood and Brain of TDMQ20, a Copper Chelator Designed as a Drug-Candidate for Alzheimer's Disease

• Үндсэн зохиолчид: Lan Huang (Зохиогч), Yaoxun Zeng (Зохиогч), Yongliang Li (Зохиогч), Yingshan Zhu (Зохиогч), Yan He (Зохиогч), Yan Liu (Зохиогч), Anne Robert (Зохиогч), Bernard Meunier (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

(1) Background: TDMQ20 is a specific regulator of copper homeostasis in the brain, able to inhibit cognitive impairment in the early stages of Alzheimer's disease (AD) in mouse models of AD. To promote the further development of this drug-candidate, preliminary data on the pharmacokinetics of T...