Inhibiting C-Reactive Protein for the Treatment of Cardiovascular Disease: Promising Evidence from Rodent Models

• Main Authors: Alexander J. Szalai (Author), Mark A. McCrory (Author), Dongqi Xing (Author), Fadi G. Hage (Author), Andrew Miller (Author), Suzanne Oparil (Author), Yiu-Fai Chen (Author), Michelle Mazzone (Author), Richard Early (Author), Scott P. Henry (Author), Thomas A. Zanardi (Author), Mark J. Graham (Author), Rosanne M. Crooke (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Raised blood C-reactive protein (CRP) level is a predictor of cardiovascular events, but whether blood CRP is causal in the disease process is unknown. The latter would best be defined by pharmacological inhibition of the protein in the context of a randomized case-control study. However, no CRP spe...