Marine-Derived Natural Products as ATP-Competitive mTOR Kinase Inhibitors for Cancer Therapeutics

• 主要な著者: Shraddha Parate (著者), Vikas Kumar (著者), Gihwan Lee (著者), Shailima Rampogu (著者), Jong Chan Hong (著者), Keun Woo Lee (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The mammalian target of rapamycin (mTOR) is a serine/threonine kinase portraying a quintessential role in cellular proliferation and survival. Aberrations in the mTOR signaling pathway have been reported in numerous cancers including thyroid, lung, gastric and ovarian cancer, thus making it a therap...