Synthesis of a Novel PTH1-34 Analog with Increased Human Serum Albumin Affinity

Abstract Parathyroid hormone (PTH)1-34 is an effective peptide drug for osteoporosis therapy. However, the half-life of PTH1-34 in vivo is short, leading to the need for frequent injections of this drug during its treatment. To prolong the half-life of PTH1-34, a novel PTH1-34 analog was generated b...

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Main Authors: Si-Da Ruan (Author), Yuan-Zhen Dong (Author), Jian-Guang Lu (Author), Meng-Jia Zhao (Author), Wei-Gen Lu (Author), Jun Feng (Author)
Format: Book
Published: Georg Thieme Verlag KG, 2021-03-01T00:00:00Z.
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