A comprehensive review of the Direct Peptide Reactivity Assay in skin sensitization testing: Applicability, limitations, and considerations

• Main Authors: Omeragić Elma (Author), Imamović Belma (Author), Dedić Mirza (Author), Mujezin Indira (Author), Bečić Ervina (Author)
• Format: Book
• Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Skin sensitization is a crucial endpoint in the safety assessment of chemicals, with the Direct Peptide Reactivity Assay (DPRA) emerging as a valuable in chemico method for evaluating a substance's sensitization potential. This review delves into the principles, applicability, and limitations o...