Eicosanoids in Cancer: Prostaglandin E2 Receptor 4 in Cancer Therapeutics and Immunotherapy

The cyclooxygenase-2 (COX-2) enzyme is frequently overexpressed in epithelial malignancies including those of the breast, prostate, lung, kidney, ovary, and liver and elevated expression is associated with worse outcomes. COX-2 catalyzes the metabolism of arachidonic acid to prostaglandins. The COX-...

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Main Authors: Mc Millan Ching (Author), Jocelyn Reader (Author), Amy M. Fulton (Author)
Format: Book
Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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