Effect of neat and binary vehicle systems on the solubility and cutaneous delivery of piperine

• Main Authors: Abdullah Hasan Alomrani (Author), Faisal Ibraheem Alhazza (Author), Khalid Mohammed AlGhamdi (Author), Gamal Mohamed El Maghraby (Author)
• Format: Book
• Published: Elsevier, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vitiligo is a skin disease characterized by depigmentation disorders due to lack of melanin production. Piperine, an alkaloid extracted from black piper, is active in melanocytes proliferation. To achieve this, the drug has to reach the melanocytes which exist in the deep layer of the epidermis. Hig...