Effects of Trough Concentration and Solute Carrier Polymorphisms on Imatinib Efficacy in Chinese Patients with Chronic Myeloid Leukemia

• Main Authors: Qing Wang (Author), Zhi-Ping Jiang (Author), Jing Zeng (Author), Yan Zhu (Author), Hua-Lin Cai (Author), Da-Xiong Xiang (Author), Qun He (Author), Xiao-Liu Shi (Author), An-Ni Zhong (Author), Xie-Lan Zhao (Author), Ping Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: We investigated the relationship between imatinib trough concentrations and genetic polymorphisms with efficacy of imatinib in Chinese patients with chronic myeloid leukemia (CML). Methods: There were 171 eligible patients. Peripheral blood samples were collected from 171 eligible patients...