Increased biogenesis of glucagon-containing secretory granules and glucagon secretion in BIG3-knockout mice

• Main Authors: Hongyu Li (Author), Tao Liu (Author), Joy Lim (Author), Natalia V. Gounko (Author), Wanjin Hong (Author), Weiping Han (Author)
• Format: Book
• Published: Elsevier, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Although both insulin and glucagon are intimately involved in the regulation of glucose homeostasis, the intrinsic control of glucagon secretion, including the biogenesis and exocytosis of glucagon-containing granules, is far less understood compared with that of insulin. As Brefeldin A-i...