Cancer-associated fibroblast infiltration in osteosarcoma: the discrepancy in subtypes pathways and immunosuppression

• Main Authors: Zhang Zhihao (Author), Ju Cheng (Author), Zuo Xiaoshuang (Author), Ma Yangguang (Author), Wu Tingyu (Author), Yang Yongyong (Author), Yao Zhou (Author), Zhou Jie (Author), Zhang Tao (Author), Hu Xueyu (Author), Wang Zhe (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Osteosarcoma (OS), the primary malignant bone tumor, has a low survival rate for recurrent patients. Latest reports indicated that cancer-associated fibroblasts (CAFs) were the main component of tumor microenvironment, and would generate a variable role in the progression of tumors. Ho...