Validation of an analytical method by high-performance liquid chromatography and microbiological assay, biological safety and in silico toxicity for danofloxacin

• Main Authors: Everson Willian Fialho Cordeiro (Author), Renata Medeiros Hilgert (Author), Luiz Alcides das Chagas Batista (Author), Raul Oliveira Souza (Author), Luís Flávio Souza de Oliveira (Author), Michel Mansur Machado (Author), Marcelo Donadel Malesuik (Author), Fávero Reisdorfer Paula (Author), Cheila Denise Ottonelli Stopiglia (Author), Clésio Soldateli Paim (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Danofloxacin is a veterinary fluoroquinolone used to treat respiratory and gastrointestinal diseases of birds, pigs and cattle. The literature reviewed shows some analytical methods to quantify this fluoroquinolone, but microbiological and biological safety studies are limited. The analytical method...