Dock-able linear and homodetic di, tri, tetra and pentapeptide library from canonical amino acids: SARS-CoV-2 Mpro as a case study

• 主要な著者: Sarfraz Ahmad (著者), Muhammad Usman Mirza (著者), John F. Trant (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2023-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Peptide-based therapeutics are increasingly pushing to the forefront of biomedicine with their promise of high specificity and low toxicity. Although noncanonical residues can always be used, employing only the natural 20 residues restricts the chemical space to a finite dimension allowing for compr...