Evidence of a New Crystalline Phase of Prednisolone Obtained from the Study of the Hydration-Dehydration Mechanisms of the Sesquihydrate

• Main Authors: Aurélien Lemercier (Author), Nicolas Couvrat (Author), Yohann Cartigny (Author), Morgane Sanselme (Author), Yohann Corvis (Author), Philippe Espeau (Author), Gérard Coquerel (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dehydration of prednisolone sesquihydrate is studied and characterized by different physico-chemical analysis methods. The meticulous study of this dehydration led to the highlighting of a new solid form (form 3), metastable, never identified before. In a second step, the rehydration of anhydrou...