Role of the 820 A/G variant in the IGF-2 gene and recurrent spontaneous abortion in southern Iran: A cross-sectional study

• Auteurs principaux: Farzaneh Ardeshir (Auteur), Leila Keshavarz (Auteur), Fatemeh Asadian (Auteur), Gohar Omidmokhtarkhanloo (Auteur), Majid Yavarian (Auteur)
• Format: Livre
• Publié: Shahid Sadoughi University of Medical Sciences, 2020-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Insulin-like growth factor-2 (IGF-2) is a polypeptide growth factor and one of the first genes expressed prior to the implantation of the embryo, with its highest expression in the placental cells. Its activity strongly depends on the genomic imprinting, and the result of the loss of gen...