Loss of PRDX6 Aborts Proliferative and Migratory Signaling in Hepatocarcinoma Cell Lines

• Main Authors: Daniel J. Lagal (Author), María J. López-Grueso (Author), José R. Pedrajas (Author), Thomas L. Leto (Author), J. Antonio Bárcena (Author), Raquel Requejo-Aguilar (Author), C. Alicia Padilla (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peroxiredoxin 6 (PRDX6), the only mammalian 1-Cys member of the peroxiredoxin family, has peroxidase, phospholipase A2 (PLA2), and lysophosphatidylcholine (LPC) acyltransferase (LPCAT) activities. It has been associated with tumor progression and cancer metastasis, but the mechanisms involved are no...