Pulmonary delivery of mucus-traversing PF127-modified silk fibroin nanoparticles loading with quercetin for lung cancer therapy

• Main Authors: Yu Tang (Author), Lanfang Zhang (Author), Rui Sun (Author), Baiyi Luo (Author), Yu Zhou (Author), Yan Zhang (Author), Yuqi Liang (Author), Bo Xiao (Author), Chenhui Wang (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The mucosal barrier remains a major barrier in the pulmonary drug delivery system, as mucociliary clearance in the airway accelerates the removal of inhaled nanoparticles (NPs). Herein, we designed and developed the inhalable Pluronic F127-modified silk fibroin NPs loading with quercetin (marked as...