Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interference.

• Main Authors: Louise Ford (Author), Jun Zhang (Author), Jing Liu (Author), Sarwar Hashmi (Author), Juliet A Fuhrman (Author), Yelena Oksov (Author), Sara Lustigman (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cathepsin-like enzymes have been identified as potential targets for drug or vaccine development in many parasites, as their functions appear to be essential in a variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion...