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Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis

Sulfation is a crucial and prevalent conjugation reaction involved in cellular processes and mammalian physiology. 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) synthase 2 (PAPSS2) is the primary enzyme to generate the universal sulfonate donor PAPS. The involvement of PAPSS2-mediated sulfa...

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Main Authors: Pengfei Xu (Author), Yue Xi (Author), Jong-Won Kim (Author), Junjie Zhu (Author), Min Zhang (Author), Meishu Xu (Author), Songrong Ren (Author), Da Yang (Author), Xiaochao Ma (Author), Wen Xie (Author)
Format: Book
Published: Elsevier, 2024-03-01T00:00:00Z.
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