Exercise sustains the hallmarks of health
Exercise has long been known for its active role in improving physical fitness and sustaining health. Regular moderate-intensity exercise improves all aspects of human health and is widely accepted as a preventative and therapeutic strategy for various diseases. It is well-documented that exercise m...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Book |
| Published: |
Elsevier,
2023-01-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_13a5f00e7d88481b96a4cfd8261a7d3f | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Yan Qiu |e author |
| 700 | 1 | 0 | |a Benjamin Fernández-García |e author |
| 700 | 1 | 0 | |a H. Immo Lehmann |e author |
| 700 | 1 | 0 | |a Guoping Li |e author |
| 700 | 1 | 0 | |a Guido Kroemer |e author |
| 700 | 1 | 0 | |a Carlos López-Otín |e author |
| 700 | 1 | 0 | |a Junjie Xiao |e author |
| 245 | 0 | 0 | |a Exercise sustains the hallmarks of health |
| 260 | |b Elsevier, |c 2023-01-01T00:00:00Z. | ||
| 500 | |a 2095-2546 | ||
| 500 | |a 10.1016/j.jshs.2022.10.003 | ||
| 520 | |a Exercise has long been known for its active role in improving physical fitness and sustaining health. Regular moderate-intensity exercise improves all aspects of human health and is widely accepted as a preventative and therapeutic strategy for various diseases. It is well-documented that exercise maintains and restores homeostasis at the organismal, tissue, cellular, and molecular levels to stimulate positive physiological adaptations that consequently protect against various pathological conditions. Here we mainly summarize how moderate-intensity exercise affects the major hallmarks of health, including the integrity of barriers, containment of local perturbations, recycling and turnover, integration of circuitries, rhythmic oscillations, homeostatic resilience, hormetic regulation, as well as repair and regeneration. Furthermore, we summarize the current understanding of the mechanisms responsible for beneficial adaptations in response to exercise. This review aimed at providing a comprehensive summary of the vital biological mechanisms through which moderate-intensity exercise maintains health and opens a window for its application in other health interventions. We hope that continuing investigation in this field will further increase our understanding of the processes involved in the positive role of moderate-intensity exercise and thus get us closer to the identification of new therapeutics that improve quality of life. | ||
| 546 | |a EN | ||
| 690 | |a Beneficial effects of exercise | ||
| 690 | |a Exercise-related physiological adaptations | ||
| 690 | |a Hallmarks of health | ||
| 690 | |a Moderate-intensity exercise | ||
| 690 | |a Therapeutic exercise | ||
| 690 | |a Sports | ||
| 690 | |a GV557-1198.995 | ||
| 690 | |a Sports medicine | ||
| 690 | |a RC1200-1245 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Journal of Sport and Health Science, Vol 12, Iss 1, Pp 8-35 (2023) | |
| 787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S209525462200103X | |
| 787 | 0 | |n https://doaj.org/toc/2095-2546 | |
| 856 | 4 | 1 | |u https://doaj.org/article/13a5f00e7d88481b96a4cfd8261a7d3f |z Connect to this object online. |