Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway

• Main Authors: Hyebeen Kim (Author), Sung Chun Cho (Author), Hyeon‐Ju Jeong (Author), Hye‐Young Lee (Author), Myong‐Ho Jeong (Author), Jung‐Hoon Pyun (Author), Dongryeol Ryu (Author), MinSeok Kim (Author), Young‐Sam Lee (Author), Minseok S. Kim (Author), Sang Chul Park (Author), Yun‐Il Lee (Author), Jong‐Sun Kang (Author)
• Format: Book
• Published: Wiley, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Muscle wasting, resulting from aging or pathological conditions, leads to reduced quality of life, increased morbidity, and increased mortality. Much research effort has been focused on the development of exercise mimetics to prevent muscle atrophy and weakness. In this study, we...