Protective Effect of Neurotrophic Agent T-817MA Against Inner Ear Barotrauma in the Guinea Pig

• Main Authors: Hitoshi Maekawa (Author), Takeshi Matsunobu (Author), Yasushi Satoh (Author), Takaomi Kurioka (Author), Asako Nakamura (Author), Noboru Iwakami (Author), Akihiro Shiotani (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}azetidin-3-ol maleate), a neurotrophic compound newly synthesized for the treatment of Alzheimer's disease, has been found to reduce oxidative stress and exert neuroprotective effects. By assessing the auditory functioning and obse...