Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever.

• Main Authors: Brian B Gowen (Author), Terry L Juelich (Author), Eric J Sefing (Author), Trevor Brasel (Author), Jennifer K Smith (Author), Lihong Zhang (Author), Bersabeh Tigabu (Author), Terence E Hill (Author), Tatyana Yun (Author), Colette Pietzsch (Author), Yousuke Furuta (Author), Alexander N Freiberg (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Junín virus (JUNV), the etiologic agent of Argentine hemorrhagic fever (AHF), is classified by the NIAID and CDC as a Category A priority pathogen. Presently, antiviral therapy for AHF is limited to immune plasma, which is readily available only in the endemic regions of Argentina. T-705 (favipirav...