Effects of JZTX-V on the wild type Kv4.3 Expressed in HEK293T and Molecular Determinants in the Voltage-sensing Domains of Kv4.3 Interacting with JZTX-V

• Үндсэн зохиолчид: Xu Dehong (Зохиогч), Wu Wenmei (Зохиогч), Hong Siqin (Зохиогч), Zeng Peng (Зохиогч), Wang Xianchun (Зохиогч), Zeng Xiongzhi (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

JZTX-V is a toxin isolated from the venom of the Chinese spider Chilobrachys jingzhao. Previous studies had shown that JZTX-V could inhibit the transient outward potassium current of Kv4.2 and Kv4.3 expressed in Xenopus oocytes but had no effects on Kv1.2-1.4. However, the underlying action mechanis...