Equine Mesenchymal Stem/Stromal Cells Freeze-Dried Secretome (Lyosecretome) for the Treatment of Musculoskeletal Diseases: Production Process Validation and Batch Release Test for Clinical Use

• Main Authors: Michela Mocchi (Author), Stefano Grolli (Author), Silvia Dotti (Author), Dario Di Silvestre (Author), Riccardo Villa (Author), Priscilla Berni (Author), Virna Conti (Author), Giulia Passignani (Author), Francesca Brambilla (Author), Maurizio Del Bue (Author), Laura Catenacci (Author), Milena Sorrenti (Author), Lorena Segale (Author), Elia Bari (Author), Pierluigi Mauri (Author), Maria Luisa Torre (Author), Sara Perteghella (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the last decades, it has been demonstrated that the regenerative therapeutic efficacy of mesenchymal stromal cells is primarily due to the secretion of soluble factors and extracellular vesicles, collectively known as secretome. In this context, our work described the preparation and characteriza...