The Protective Effects of Erythropoietin on Rat Glomerular Podocytes in Culture are Modulated by Extracellular Matrix Proteins

• Main Authors: Jan Krtil (Author), Jan Pláteník (Author), Nikola Čuřík (Author), Wunnie Brima (Author), Vladimír Tesař (Author), Tomáš Zima (Author)
• Format: Book
• Published: Karger Publishers, 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Podocytes are typically cultured on collagen I; however, collagen I is absent from healthy glomerular basement membranes. Erythropoietin (EPO) is thought to protect podocytes in vivo. Here, we studied how various types of extracellular matrix (ECM) proteins and EPO affect podocytes...