A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adults

• Main Authors: Geert Leroux-Roels (Author), Maria Lattanzi (Author), Claudia Dovali Solis (Author), Mario Contorni (Author), Marco Costantini (Author), Luca Moraschini (Author), Monia Bardelli (Author), Sylvie Bertholet (Author), Erica Borgogni (Author), Francesca Buricchi (Author), Rocco Cantisani (Author), Elisa Faenzi (Author), Oretta Finco (Author), Rosanna Leuzzi (Author), Mariagrazia Pizza (Author), Domenico Rosa (Author), Francesca Schiavetti (Author), Anja Seubert (Author), Fabiana Spensieri (Author), Gianfranco Volpini (Author), Luisanna Zedda (Author), Giuseppe Del Giudice (Author), Ilaria Galgani (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite high vaccination coverage worldwide, pertussis has re-emerged in many countries. This randomized, controlled, observer-blind phase I study and extension study in Belgium (March 2012-June 2015) assessed safety and immunogenicity of investigational acellular pertussis vaccines containing genet...