Emerging antioxidant therapies in Friedreich's ataxia

• Main Authors: Fred Jonathan Edzeamey (Author), Zenouska Ramchunder (Author), Charareh Pourzand (Author), Sara Anjomani Virmouni (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Friedreich's ataxia (FRDA) is a rare childhood neurologic disorder, affecting 1 in 50,000 Caucasians. The disease is caused by the abnormal expansion of the GAA repeat sequence in intron 1 of the FXN gene, leading to the reduced expression of the mitochondrial protein frataxin. The disease is c...