Release of Danger Signals during Ischemic Storage of the Liver: A Potential Marker of Organ Damage?

• Main Authors: Anding Liu (Author), Hao Jin (Author), Olaf Dirsch (Author), Meihong Deng (Author), Hai Huang (Author), Martina Bröcker-Preuss (Author), Uta Dahmen (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver grafts suffer from unavoidable injury due to ischemia and manipulation before implantation. Danger signals such as high-mobility group box -1(HMGB1) and macrophage migration inhibitory factor (MIF) play a pivotal role in the immune response. We characterized the kinetics of their release into...