First third-generation CAR T cell application targeting CD19 for the treatment of systemic IgM AL amyloidosis with underlying marginal zone lymphoma

• Main Authors: Felix Korell (Author), Stefan Schönland (Author), Anita Schmitt (Author), Madelaine Jansen (Author), Kiavasch Farid (Author), Carsten Müller-Tidow (Author), Peter Dreger (Author), Michael Schmitt (Author), Ute Hegenbart (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Light chain amyloidosis (AL) is a rare disease caused by the generalized deposition of misfolded free light chains. Patients with immunoglobulin M gammopathy (IgM) and indolent B-cell lymphoma such as marginal zone lymphoma (MZL) may in some instances develop AL amyloidosis. So far, CAR T c...