High intrapatient variability of tacrolimus exposure associated with poorer outcomes in liver transplantation

• Main Authors: Cristina Dopazo (Author), Itxarone Bilbao (Author), Sonia García (Author), Concepción Gómez‐Gavara (Author), Mireia Caralt (Author), Isabel Campos‐Varela (Author), Lluis Castells (Author), Ernest Hidalgo (Author), Francisco Moreso (Author), Bruno Montoro (Author), Ramón Charco (Author)
• Format: Book
• Published: Wiley, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tacrolimus (TAC) is a dose‐dependent immunosuppressor with considerable intrapatient variability (IPV) in its pharmacokinetics. The aim of this work is to ascertain the association between TAC IPV at 6 months after liver transplantation (LT) and patient outcome. This single‐center cohort st...