Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells

• প্রধান লেখক: Dido Carrero (লেখক), Clara Soria-Valles (লেখক), Carlos López-Otín (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: The Company of Biologists, 2016-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Ageing is a process that inevitably affects most living organisms and involves the accumulation of macromolecular damage, genomic instability and loss of heterochromatin. Together, these alterations lead to a decline in stem cell function and to a reduced capability to regenerate tissue. In recent y...