Safranal, an active constituent of saffron, ameliorates myocardial ischemia via reduction of oxidative stress and regulation of Ca2+ homeostasis

• Main Authors: Yurun Xue (Author), Weiyue Jin (Author), Yucong Xue (Author), Yuanyuan Zhang (Author), Hongfang Wang (Author), Yixin Zhang (Author), Shengjiang Guan (Author), Xi Chu (Author), Jianping Zhang (Author)
• Format: Book
• Published: Elsevier, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Safranal (SFR) is the major constituent of saffron. The purpose of this study was to observe the effect of SFR on myocardial ischemia induced by isoprenaline (ISO) and to explore its possible mechanism. The myocardial ischemia rat model was established by subcutaneous injection of ISO (85 mg/kg/d) o...