Protein Phosphatase Magnesium-Dependent 1δ (PPM1D) Expression as a Prognostic Marker in Adult Supratentorial Diffuse Astrocytic and Oligodendroglial Tumors

• Main Authors: Hui Jeong Jeong (Author), Chang Gok Woo (Author), Bora Lee (Author), Shin Kwang Khang (Author), Soo Jeong Nam (Author), Jene Choi (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Protein phosphatase magnesium-dependent 1δ (PPM1D) is a p53-induced serine/threonine phosphatase, which is overexpressed in various human cancers. A recent study reported that a mutation in the PPM1D gene is associated with poor prognosis in brainstem gliomas. In this study, we evaluated...