Prevalence of pathogenetic MC4R mutations in Italian children with early Onset obesity, tall stature and familial history of obesity

• Main Authors: Crinò Antonino (Author), Balsamo Antonio (Author), Di Pietro Mario (Author), Salvatoni Alessandro (Author), Vottero Alessandra (Author), Iughetti Lorenzo (Author), Morino Giuseppe (Author), Greggio Nella (Author), Tanas Rita (Author), Xiang Zhimin (Author), Cirillo Grazia (Author), Santoro Nicola (Author), Grandone Anna (Author), Haskell-Luevano Carrie (Author), Perrone Laura (Author), del Giudice Emanuele (Author)
• Format: Knjiga
• Izdano: BMC, 2009-03-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Melanocortin-4-receptor (MC4R) mutations represent the most frequent genetic cause of non-syndromic early onset obesity. Children carrying MC4R mutations seem to show a particular phenotype characterized by early onset, severe obesit...