Impeding the combination of astrocytic ASCT2 and NLRP3 by talniflumate alleviates neuroinflammation in experimental models of Parkinson's disease

• Main Authors: Yang Liu (Author), Ting Liu (Author), Yuanzhang Zhou (Author), Wenjie Li (Author), Min Wang (Author), Nanshan Song (Author), Wenbin Zhang (Author), Jingwei Jiang (Author), Shengtao Yuan (Author), Jianhua Ding (Author), Gang Hu (Author), Ming Lu (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alanine-serine-cysteine transporter 2 (ASCT2) is reported to participate in the progression of tumors and metabolic diseases. It is also considered to play a crucial role in the glutamate-glutamine shuttle of neuroglial network. However, it remains unclear the involvement of ASCT2 in neurological di...