ICR suckling mouse model of Zika virus infection for disease modeling and drug validation.

• Main Authors: Yu-Hsuan Wu (Author), Chin-Kai Tseng (Author), Chun-Kuang Lin (Author), Chih-Ku Wei (Author), Jin-Ching Lee (Author), Kung-Chia Young (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Zika virus (ZIKV) infection causes diseases ranging from acute self-limiting febrile illness to life-threatening Guillain-Barré Syndrome and other neurological disorders in adults. Cumulative evidence suggests an association between ZIKV infection and microcephaly in newborn infants. Giv...