Enhancing the chemotherapy effect of Apatinib on gastric cancer by co-treating with salidroside to reprogram the tumor hypoxia micro-environment and induce cell apoptosis

• Main Authors: Zhandong Zhang (Author), Wei Yang (Author), Fei Ma (Author), Qi Ma (Author), Bin Zhang (Author), Yonglei Zhang (Author), Yingqiang Liu (Author), Hongxing Liu (Author), Yawei Hua (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypoxic microenvironment commonly occurred in the solid tumors considerably decreases the chemosensitivity of cancer cells. Salidroside (Sal), the main active ingredient of Rhodiola rosea, was shown to be able of regulating the tumor hypoxia micro-environment and enhancing the chemotherapeutic effic...