Computational drug discovery of potential TAU protein kinase I inhibitors using in silico docking studies

• Main Authors: Arumugam Madeswaran (Author), Muthuswamy Umamaheswari (Author), Kuppusamy Asokkumar (Author), Thirumalaisamy Sivashanmugam (Author), Varadharajan Subhadradevi (Author), Puliyath Jagannath (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of the current study is to evaluate the tau protein kinase I inhibitory activity of flavonoids using in silico docking studies. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm principle. Memantine, a known neuro-receptor antagoni...