Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity

• Main Authors: M. Ali (Author), Assem Barakat (Author), Ayman El-Faham (Author), Hessa H. Al-Rasheed (Author), Kholoud Dahlous (Author), Abdullah Mohammed Al-Majid (Author), Anamika Sharma (Author), Sammer Yousuf (Author), Mehar Sanam (Author), Zaheer Ul-Haq (Author), M. Iqbal Choudhary (Author), Beatriz G. de la Torre (Author), Fernando Albericio (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new series of thiobarbituric (thiopyrimidine trione) enamine derivatives and its analogues barbituric acid derivatives was synthesised, characterised, and screen for in vitro evaluation of α-glucosidase enzyme inhibition and anti-glycation activity. This series of compounds were found to inhibit α...