The first Dutch <it>SDHB </it>founder deletion in paraganglioma - pheochromocytoma patients

• Main Authors: Devilee Peter (Author), Dullaart Robin PF (Author), Jansen Jeroen C (Author), Lenders Jacques W (Author), Kunst Henricus P (Author), van der Wielen Michiel (Author), van Bunderen Patrick A (Author), Grimbergen Anneliese EM (Author), Bayley Jean-Pierre (Author), Corssmit Eleonora P (Author), Vriends Annette H (Author), Losekoot Monique (Author), Weiss Marjan M (Author)
• Format: Book
• Published: BMC, 2009-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Germline mutations of the tumor suppressor genes <it>SDHB, SDHC </it>and <it>SDHD </it>play a major role in hereditary paraganglioma and pheochromocytoma. These three genes encode subunits of succinate dehydro...