Yuan-Zhi decoction in the treatment of Alzheimer's disease: An integrated approach based on chemical profiling, network pharmacology, molecular docking and experimental evaluation

• Main Authors: Qiong Wu (Author), Xiang Li (Author), Xiao-Wen Jiang (Author), Dong Yao (Author), Li-Jun Zhou (Author), Zi-Hua Xu (Author), Nan Wang (Author), Qing-Chun Zhao (Author), Zhou Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Yuan-Zhi Decoction (YZD) is a traditional Chinese medical formulation with demonstrated clinical benefits in Alzheimer's disease (AD). We used liquid chromatography coupled with mass spectrometry to identify 27 unique chemical components of YZD. Analyzing these using network pharmacology and mo...