Live imaging of osteoclast inhibition by bisphosphonates in a medaka osteoporosis model

• Main Authors: Tingsheng Yu (Author), Paul Eckhard Witten (Author), Ann Huysseune (Author), Anita Buettner (Author), Thuy Thanh To (Author), Christoph Winkler (Author)
• Formato: Libro
• Publicado: The Company of Biologists, 2016-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Osteoclasts are bone-resorbing cells derived from the monocyte/macrophage lineage. Excess osteoclast activity leads to reduced bone mineral density, a hallmark of diseases such as osteoporosis. Processes that regulate osteoclast activity are therefore targeted in current osteoporosis therapies. To i...