Loss of NF2 defines a genetic subgroup of non‐FOS‐rearranged osteoblastoma

• Main Authors: Karim H Saba (Author), Louise Cornmark (Author), Jakob Hofvander (Author), Linda Magnusson (Author), Jenny Nilsson (Author), Hilda van denBos (Author), Diana CJ Spierings (Author), Floris Foijer (Author), Johan Staaf (Author), Otte Brosjö (Author), Vaiyapuri P Sumathi (Author), Suk Wai Lam (Author), Karoly Szuhai (Author), Judith VMG Bovée (Author), Michal Kovac (Author), Daniel Baumhoer (Author), Emelie Styring (Author), Karolin H Nord (Author)
• Format: Book
• Published: Wiley, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Osteoblastoma is a locally aggressive tumour of bone. Until recently, its underlying genetic features were largely unknown. During the past two years, reports have demonstrated that acquired structural variations affect the transcription factor FOS in a high proportion of cases. These rearr...