Antioxidant Polyphenols of <i>Antirhea borbonica</i> Medicinal Plant and Caffeic Acid Reduce Cerebrovascular, Inflammatory and Metabolic Disorders Aggravated by High-Fat Diet-Induced Obesity in a Mouse Model of Stroke

• Hoofdauteurs: Janice Taïlé (Auteur), Matthieu Bringart (Auteur), Cynthia Planesse (Auteur), Jessica Patché (Auteur), Philippe Rondeau (Auteur), Bryan Veeren (Auteur), Patricia Clerc (Auteur), Anne Gauvin-Bialecki (Auteur), Steeve Bourane (Auteur), Olivier Meilhac (Auteur), David Couret (Auteur), Marie-Paule Gonthier (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Metabolic disorders related to obesity and type 2 diabetes are associated with aggravated cerebrovascular damages during stroke. In particular, hyperglycemia alters redox and inflammatory status, leading to cerebral endothelial cell dysfunction, blood-brain barrier (BBB) disruption and brain homeost...