Hydrogen Sulfide Promotes Thyroid Hormone Synthesis and Secretion by Upregulating Sirtuin-1

• Main Authors: Xue Zhao (Author), Yedi Cao (Author), Hongfang Jin (Author), Xiuli Wang (Author), Lanbo Zhang (Author), Yang Zhang (Author), Yang Yu (Author), Youyuan Huang (Author), Ying Gao (Author), Junqing Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: One mechanism of hypothyroidism involves the disruption of thyroid hormone synthesis and secretion by thyrocytes. Hydrogen sulfide (H2S), as a gas signaling molecule, participates in many physiopathologic processes by upregulating sirtuin-1 (SIRT1). The aim of the current study was to exp...