Multiple Origins of Mutations in the mdr1 Gene--A Putative Marker of Chloroquine Resistance in P. vivax.

• मुख्य लेखकों: Mette L Schousboe (लेखक), Samir Ranjitkar (लेखक), Rupika S Rajakaruna (लेखक), Priyanie H Amerasinghe (लेखक), Francisco Morales (लेखक), Richard Pearce (लेखक), Rosalyn Ord (लेखक), Toby Leslie (लेखक), Mark Rowland (लेखक), Nahla B Gadalla (लेखक), Flemming Konradsen (लेखक), Ib C Bygbjerg (लेखक), Cally Roper (लेखक), Michael Alifrangis (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2015-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

BACKGROUND:Chloroquine combined with primaquine has been the recommended antimalarial treatment of Plasmodium vivax malaria infections for six decades but the efficacy of this treatment regimen is threatened by chloroquine resistance (CQR). Single nucleotide polymorphisms (SNPs) in the multidrug res...