Evaluation of Human Peroxisome Proliferator-Activated Receptor (PPAR) Subtype Selectivity of a Variety of Anti-inflammatory Drugs Based on a Novel Assay for PPARδ(β)

• Main Authors: Hitoshi Kojo (Author), Masao Fukagawa (Author), Kaoru Tajima (Author), Akiko Suzuki (Author), Takao Fujimura (Author), Ichiro Aramori (Author), Ken-ichi Hayashi (Author), Shintaro Nishimura (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: The nuclear receptor PPAR (peroxisome proliferator-activated receptor) has three subtypes named α, δ(β), and γ that may act as receptors for a range of compounds including antihyperglycaemic drugs, insulin sensitizers, and non-steroidal anti-inflammatory drugs (NSAIDs). Although profiling...