Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic

• Main Authors: Marion T.J. van den Bosch (Author), Sanaz Yahyanejad (Author), Mir Farshid Alemdehy (Author), Bryony J. Telford (Author), Thijs de Gunst (Author), Harm C. den Boer (Author), Rogier M. Vos (Author), Marieke Stegink (Author), Laurens A.H. van Pinxteren (Author), Roel Q.J. Schaapveld (Author), Michel Janicot (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Emerging data show that microRNA 193a-3p (miR-193a-3p) has a suppressive role in many cancers and is often downregulated in tumors, as compared to surrounding normal tissues. Therefore, mimics of miR-193a-3p could be used as an attractive therapeutic approach in oncology. To better understand and do...