Pregabalin reduces cisplatin-induced mechanical allodynia in rats

• Ngā kaituhi matua: Yoshihiro Seto (Author), Miyuki Takase (Author), Yasuhiro Tsuji (Author), Hideto To (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2017-07-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Although cisplatin (CDDP) is a key drug in cancer chemotherapy, CDDP-induced peripheral neuropathy is a dose-limiting factor. We previously reported that CDDP-induced peripheral neuropathy, which progressed from allodynia to hypoalgesia, was ameliorated by the administration of CDDP to rats at a spe...